SCIENTIFIC UPDATE

By Reed Mangels, PhD, RD

Animal Product-Based, Low Carb Diets Associated with Shorter Lifespan
Low carb diets are frequently touted as a way to lose weight or to improve overall health. In reality, although some short-term weight loss may occur, these diets are associated with a higher risk of death. Beginning in 1987, researchers enrolled more than 15,000 U.S. middle-aged adults in a study that continued for about 25 years. The study subjects were asked about their diet periodically. Records were kept of which subjects died during the study period. Those subjects who had the lowest (less than 40% of calories) and the highest (more than 60%) intakes of carbohydrates were markedly more likely to die than were subjects whose carbohydrate intake was in the middle — around 50-55% of calories coming from carbohydrates. The researchers calculated that a 50-year old person whose diet had less than 30% calories from carbohydrate would reduce their projected life expectancy by four years compared to what would be expected if their diet had more carbohydrate. A very high carbohydrate diet had a similar but smaller effect — a reduction in projected life expectancy of 1.1 years. The researchers hypothesized that many of the very high carbohydrate diets were high in refined carbohydrates (sugars, white bread, white rice, etc.) and not high in whole grains. This study found that, if dietary carbohydrate was reduced and animal-based protein and fat were used to replace carbohydrate, risk of death increased. If plant-based protein and fat replaced carbohydrate, risk of death decreased. This study suggests that, if someone chooses to reduce carbohydrate, it's better to replace it with plant-based protein and fat. Low carb-high animal product diets aren't a good choice.

Seidelmann SB, Claggett B, Cheng S, et al. 2018. Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis. Lancet Public Health. 3(9):e419-e428.

Vitamin B12 in Vegan Women's Breast Milk
Getting enough vitamin B12 is especially important for infants and young children because of this vitamin's role in nervous system development. Breastfed infants rely on their mothers' milk to supply vitamin B12. A recent study found that the concentration of vitamin B12 in breast milk from vegans was similar to that of non-vegans. This study examined 26 vegans, 22 lacto-ovo or lacto vegetarians, and 26 non-vegetarians. All but two of the vegans used a vitamin B12 supplement. Approximately 20% of all the women had milk vitamin B12 concentrations that were described as low; however, the adequate concentration of vitamin B12 in breast milk has not been firmly established. Vegans were no more likely to have low milk vitamin B12 concentrations than were non-vegans. This study suggests that vegans who use vitamin B12 supplements will have breast milk vitamin B12 concentrations similar to those of non-vegans.

Pawlak R, Vos P, Shahab-Ferdows S, Hampel D, Allen L, Perrin M. 2018. Vitamin B-12 content in breast milk of vegan, vegetarian, and non-vegetarian lactating women in the United States. Am J Clin Nutr. 146: 1125?1131.

Supplements and Fortified Non-Dairy Milks Provide Vitamin B12 to Vegetarians
Where do vegetarians get vitamin B12? A study of Seventh-day Adventists examined practices of 728 adults. Vegans (defined as never or rarely eating meat, fish, dairy, and eggs) were 9% of the study subjects, 28% were lacto-ovo vegetarians (defined as never or rarely eating meat or fish), and the remainder were non-vegetarians. Overall, about 60% of study subjects used a vitamin B12 supplement. Those using vitamin B12 supplements had significantly higher blood vitamin B12 concentrations than those not using supplements. As might be expected, vegetarians and vegans had a higher intake of vitamin B12 from fortified foods than did non-vegetarians. Non-dairy milks fortified with vitamin B12 had a positive effect on blood vitamin B12 concentrations in those subjects who did not use vitamin B12 supplements. On average, fortified foods supplied enough vitamin B12 to meet recommendations for vitamin B12. These results suggest that this population of vegans and vegetarians is aware of the need for adequate vitamin B12 and is using supplements and fortified foods to supply this essential nutrient.

Damayanti D, Jaceldo-Siegl K, Beeson WL, Fraser G, Oda K, Haddad EH. 2018. Foods and supplements associated with vitamin B12 biomarkers among vegetarian and non-vegetarian participants of the Adventist Health Study-2 (AHS-2) Calibration Study. Nutrients. 10(6). pii: E722.

Linking Dietary Choices to Climate Change
Researchers at the University of Michigan and Tulane University developed a new database, dataFIELD, to better approximate the environmental impacts of dietary choices.1 This is the first attempt to estimate the total greenhouse gas emissions and comprehensive energy demand (amount of energy needed to create a product) from self-selected diets (what people actually eat) in the U.S.

The researchers found that, on average, 4.7 kilograms of carbon dioxide are produced per day from the food a person in the U.S. eats. This greenhouse gas comes from food production, transportation, and ingredient processing. Compare this to the average passenger car emission of 404 grams (0.404 kilograms) of carbon dioxide per mile.2 This study suggests that, in the U.S., meat is responsible for 56.6% of the total greenhouse gas emissions from diet, followed by dairy, which is responsible for 18.3%.1 Vegetables, grains, legumes, and fruits each individually account for less than 3% of the total greenhouse gas emissions from diet.

The environmental impact of the highest greenhouse gas producing diets is eight times higher than that of the lowest greenhouse gas producing diets. Almost three-quarters of the greenhouse gas emissions attributed to the highest greenhouse gas producing diets are due to meat, specifically beef. According to the researchers, "If the top quintile of diets (representing 44.6 million Americans on a given day) shifted such that their associated GHGE [greenhouse gas emissions] were aligned with the mean [average] impact, this would represent a one-day reduction in GHGE of 0.27 million metric tons CO2 eq. (mmt), equivalent to eliminating 661 million average passenger vehicle miles on a given day."1

Dietary change, meaning lower calorie intake and/or less meat and dairy consumption, is an effective way to reduce greenhouse gas emissions and thus climate change.

1 Heller MC, Willits-Smith A, Meyer R, Keoleian GA, Rose D. 2018. Greenhouse gas emissions and energy use associated with production of individual self-selected US diets. Environ Res Lett. 13(4):044004.

2 EPA. Greenhouse gas emissions from a typical passenger vehicle. www.epa.gov/greenvehicles/greenhouse-gas-emissions-typical-passenger-vehicle. Accessed 25 June 2018.

By Amy Dell, VRG Intern

Eat More Plant Foods to Reduce Cancer Risk Says Expert Panel
The World Cancer Research Fund Network recently issued their third evidence-based report on cancer prevention. The expert panel that developed these recommendations concluded that a marked reduction in cancer occurrence worldwide could be achieved by "avoidance of tobacco in any form, together with appropriate diet and nutrition, physical activity, and maintaining a healthy weight." Specifically, the report calls for eating a diet high in plant foods and making whole grains, fruits, vegetables, and legumes a major part of the usual daily diet. Processed meat should be completely avoided, and red meat, if eaten, limited to no more than three servings a week. While the report did not specifically endorse vegan diets, it clearly made a case for eating mainly whole, plant-based foods to reduce the risk of cancer.

World Cancer Research Fund/American Institute for Cancer Research. Diet, Nutrition, Physical Activity and Cancer: a Global Perspective. Continuous Update Project Expert Report, 2018. Available at www.dietandcancerreport.org